Roids roids roids

What three organs in the body control the endogenous production of glucocorticoid and androgen hormones? [No commas needed]

Which of the following statements is TRUE?

• Decreasing the dose of long-term systemic corticosteroids too quickly, without tapering, can result to adrenal insufficiency

• Ideal exogenous glucocorticoids are those that likewise have mineralocorticoid effects

• Steroids should be given before dinner to mimic the normal diurnal sleep-wake cycle

• Twice daily dosing is the preferred frequency for oral steroids

Which topical corticosteroid has the lowest IOP increasing effect?

• Dexamethasone

• Fluorometholone

• Loteprednol

• Rimexolone

You decide to give 1 gram IV Methylprednisolone to your patient with acute VKH. Unfortunately, methylprednisolone is not available in your hospital pharmacy, and you resort to giving oral Prednisone instead. What is the equivalent dose of 1 gram methylprednisolone to prednisone? [NOTE: the potency of Prednisone is only 80% of Methylprednisolone]

• 800mg

• 1000mg

• 1250mg

• 1500mg

What morphologic type of cataract is commonly associated with corticosteroid use?

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Which of the following is/are systemic side effect/s of corticosteroid therapy? Check all that apply.

• Acne

• Hypoglycemia

• Osteonecrosis

• Sexual lability

• Weight loss

Determine which of the following pairs of parameters and monitoring frequency schedules is properly matched.

• Blood pressure : Weekly

• Height : Monthly

• HbA1c : Quarterly

• Bone densitometry scan : Bi-annually

A 32 year-old 6 months pregnant patient comes in for acute onset of floaters and blurring of vision on the right eye. You assessed her as a case of intermediate uveitis with macular edema and optic disc edema. You decide to treat with systemic corticosteroids due to her steroid responsive nature. What should you advise her?

• Exogenous steroids are classified as US-FDA pregnancy category A, it is safe to use.

• Exogenous steroids are classified as US-FDA pregnancy category C, benefits outweigh potential risks.

• She cannot breastfeed since corticosteroid particles can accumulate in breast milk, causing too much exogenous steroid intake for the infant.

• There will be no reduction in milk supply post-partum.

How long is the approximate duration of the treatment effect of triamcinolone if injected in the periocular space?

• Up to 6 weeks

• Up to 12 weeks

• Up to 16 weeks

• Up to a year

Which of the following are considered risk factors predisposing a patient to steroid-induced IOP elevation? Check all that apply.

• Connective tissue disease

• Diabetes mellitus

• Hyperopia

• Young age