Tetracycline

Popular trait of tetracycline

• Stable in pH > 7

• Dissolve in lipid

• Kelate (Ca, Mg..)

• The most toxicity drug

Tetracycline usually stored in

• Brain

• Bone

• Teeth

• B & C correct

Doxycycline & Minocycline

• Store more in bones

• Store more in tooth

• Dissolve more in lipid

• Dissolve more in water

Yellowed teeth after using tetracycline in newborn

• Tetracycline magnesium- orthophosphat

• Tetracycline ion- orthophosphat

• Tetracycline calcium-orthophosphat

• Tetracycline sodium-orthophosphat

Spectrum of tetracycline

• G+

• G-

• Mycoplasma spp, Protozoa

• All correct

Doxycycline & Minocycline often used to treat

• Uterus infection

• UTI

• Indigestion infection

• Prostate infection

Why using tetracycline in a long time leads to mold-superinfection

• Missing Vit A, C

• Missing Vit B, C

• Missing Vit B, K

• Missing Vit C, D

Which substances or matters decrease tetracycline's effect

• Kaolin

• Pectin

• Bismuth subsalicylate

• All correct

Answer explanation

Kaolin, Pectin: absorps toxicity, fluid

Mechanism of tetracycline

• To bind 50S

• To bind 30S

• To stop tRNA bind to mRNA

• All correct

Tetracycline is a......drug

• bacteriostatic

• bactericidal

• bacteriostatic/bactericidal

• All correct