CC2LAB

Which is oxidized?

(capital letter)

Reference Range of Lactate Dehydrogenase (LD/LDH)

• 225 - 230 IU/L

• 125 - 220 IU/L

• 130 - 250 IU/L

• 145 - 225 IU/L

directly affects the heart (cardiac muscle tissues)

manifests as agina or Myocardial infarction and heart attack/acute myocardial infarction

• Coronary Heart Disease

• Cerebrovascular Disease

• Peripheral Arterial Disease

• Aortic Atherosclerotic Disease

- vessels of the brain

- stroke and transient ischemic attacks (temporary paralysis)

• Coronary Heart Disease

• Cerebrovascular Disease

• Peripheral Arterial Disease

• Aortic Atherosclerotic Disease

- deficiency in peripheral region like arms of legs

- acute localized pain to the arms and legs

• Coronary Heart Disease

• Cerebrovascular Disease

• Peripheral Arterial Disease

• Aortic Atherosclerotic Disease

- formation of plaque

• Coronary Heart Disease

• Cerebrovascular Disease

• Peripheral Arterial Disease

• Aortic Atherosclerotic Disease

Methods for LD/LDH

* not very specific and very sensitive measurement for LD activity

• Chemical inhibition: alpha hydroxybutyrate

• Wacker (pH 8.3-8.9)

• Wroblewski La Due (pH 7.1 - 7.4)

Methods for LD/LDH

* more alkaline and almost neutral

* Lactate to pyruvate

* Increasing absorbance pattern

• Chemical inhibition: alpha hydroxybutyrate

• Wacker (pH 8.3-8.9)

• Wroblewski La Due (pH 7.1 - 7.4)

Methods for LD/LDH

* decreasing

* Preferred method

* 3x faster than forward

• Chemical inhibition: alpha hydroxybutyrate

• Wacker (pH 8.3-8.9)

• Wroblewski La Due (pH 7.1 - 7.4)

* Forward Method

*pH = 9

* Alkaline

* Decreasing

• Oliver - Rosalki

• Tanzer - Gilvarg