Lecture 17

What is typically performed during the first trimester and again in the second trimester, as a test for 19 different congenital diseases?

• MaterniT21

• Non-invasive Prenatal tests

• Karyotyping

• Chrorionic villus sampling (CVS)

How does MaterniT21 Plus work?

• Measures relative amounts of different chromosomal material by NGS

• Detects down syndrome in fetal DNA from blood

• isolate and culture fetal cells from blood

Chronic myelogenous leukemia (CML) can be detected by

• karyotyping

• NGS

• Gel Electrophoresis

• FISH

Tumor-Suppressor Genes (TSG) normally has what job?

• Causes cells to divide excessively

• Causes cell death

• Inhibits cell division

• Activates cell division

What is one positive outcome from personalized medicine?