Ryzodeg QUIZ April 2023

If a dose of Ryzodeg® is missed from the usual schedule, the patient can take the missed dose at

• After 24 Hours from the missed dose

• At same time at next Day

• Next main meal of that day

• Must take after 42 Hours

The duration of action of a single-dose of Ryzodeg® is beyond ?

• 18 Hours

• 24 Hours

• 4-6 Hours

• None of these

The half-life of the basal component (insulin degludec) at steady state is ____ hours independent of dose ?

• 13 Hours

• 25 Hours

• Upto 42 Hours

• All of these

The amino acid sequence of Insulin Degludec is identical to human insulin except for removal of threonine at _______ and at _______, a glutamic acid spacer is attached that bridges to a _______________.

• B29, B30, 16 carbon diacid chain

• B30, B29, 16 carbon diacid chain

• A21, B30, 16 carbon diacid chain

The pk & clearance of IDegAsp are not impaired in patients with mild, moderate or severe renal or hepatic impairment and can be used in these patients safely.

• True

• False

What should be the minimum time gap between the two doses of IDegAsp?

• 4 Hours

• 4 to 6 Hours

• 8 to 10 Hours

• at least 24 Hours

Bright trial is the head to head comparison of Insulin Degludec and Insulin Glargine U100.

• True

• False

Rate of treatment discontinuation in Degludec arm is bright trial was ?

• 4.1%

• 5.2%

• 6%

• 6.5%

In Bright trial overall , ___ of patients reached HbA1c < 7% target.

• 42%

• 44%

• 47%

• 54%

____ lower daily insulin dose with degludec compared with glargine U300 at bright trial end.

• 17%

• 20%

• 30%

• 9%