CHAPTER 12 - The Adrenal Gland

Signs such as “buffalo hump” and “moon face” is evident in which disease?

• Hyperaldosteronism

• Androgen excess

• Adrenal insufficiency

• Hypercortisolism

Tags

NGSS.HS-LS1-3

What is the ratio of NE to EPI in the serum?

• 1:9

• 1:2

• 9:1

•  2:1

What test is used in the biochemical testing of Pheochromocytoma and Paraganglioma?

• 24-hour Urine Free Cortisol

• Saline infusion test

• 24-hour Urine Fractionated Metanephrines and Catecholamines

•  Insulin Tolerance Test

Which of the following is not true about two-site IRMA?

• If the 8 am ACTH level is greater than 5 ug/dL, cortisol secretion is considered ACTH dependent.

• Used to determine the reason for high cortisol levels

• ACTH less than 5 ug/dL, cortisol secretion is thought to be ACTH dependent.

• Used to determine the reason for low cortisol levels

Which is the Gold standard for determining source of ACTH production?

• two-site IRMA

• Inferior Petrosal Sinus Sampling

• Late night salivary cortisol level

• Dexamethasone Suppression Test

What part of the microscopic anatomy of the adrenal glands synthesizes glucocorticoids and is critical for homeostasis and balance of glucose?

• Zona Reticularis

• Zona Glomerulosa

• Zona Reticularis

• Adrenal Medulla

Tags

NGSS.HS-LS1-3

Catecholamine degradation relies on which enzymes?

• Catechol methyltransferase

• Monoamine oxidase

• Both 

• None of the above

Most common endocrine disorder in women of reproductive age

• Hypercortisolism

• Hyperaldosteronism

• Androgen Deficiency

• Androgen Excess

Tags

NGSS.HS-LS1-3

The following are true about the Adrenal Medulla except;

• Acts as first responder to stress to promote fight or flight response

• Produced in large amounts and extremely potent, rapidly activated

• Site of formation for sympathetic neuron (CNS)

• Produces catecholamines

It is the end metabolite in the urine in catecholamine degradation:

• free nonepinephrine

• conjugated nonepinephrine

• metanephrine

• vanilylmandelic acid