Test 16 mln continues

Match the following

• Sezary Cell

• 
• Hairy cell in Peripheral Blood (PB)

• 
• "starry eyed" appearance revealed in biopsy

• 
• tumor

• 
• "fried egg" in Bone Marrow (BM)

• 

Chronic Lymphocytic Leukemia (CLL)

A ​ (a)   lymphoid leukemia - ​ (b)  

Median age: ​ (c)   2 times ​ (d)   in men than in women

diagnosis: absolute lymphocytosis ​ (e)   characteristic morphologic traits

• chronic
• B cells
• 70
• more common
• plus
• 80
• minus
• T cells
• acute

Which of these are not found in Chronic Lymphocytic Leukemia (CLL)?

• anemia

• thrombocytopenia

• Pancytopenia

• neutropenia

In Chronic Lymphocytic Leukemia (CLL) diagnosis there is an absolute lymphocytosis plus characteristic morphologic traits. Which of the following are not used in the diagnosis?

• "Hairy cells" in PB, but WBC not usually elevated.

• majority small "hyper-mature" lymphs

• a few prolymphocytes

• smudge cells (add 1 drop of albumin to 1 drop PB)

Match the following

• "cerebriform" nucleus in Sezary Syndrome

• Sezary Syndrome

• BM infiltrated by mature plasma cells

• brainlike

• CD23+

  CLL

• B cell

• CD5

  CLL

• Multiple myeloma

• a cutaneous chronic T cell lymphoma

• T cell

Choose all of the characteristics of Hairy Cell Leukemia (HCL).

• thrombocytopenia, neutropenia

• a chronic lymphoid leukemia - B cells

• presents in middle age; male predominance

• massive splenomegaly but no lymphadenopathy

• Pancytopenia

Hairy Cell Leukemia (HCL)

​ (a)   lymphs have cytoplasmic ​ (b)  

“Hairy cells” in ​ (c)   , but WBC not usually ​ (d)  

“Fried egg” appearance in BM

TRAP +

Highly positive for ​ (e)   : 11c, 25, 103, 123

Chemo

• Neoplastic
• protrusions
• PB
• elevated
• CD markers

Which of these are NOT part of identifying Sezary Syndrome?

• Erythroderma

• Generalized lymphdenopathy

• Abnormal T cells in skin, lymph nodes and PB

• presents in middle age; male predominance

Mycosis ​ (a)  

Sézary cells in ​ (b)   – “cerebriform” nucleus

​ (c)   , CD4+, ​ (d)  

Treatment usually ​ (e)   , to relieve symptoms

• fungoides
• circulation
• CD3+
• CD7-
• palliative
• CD5+
• CD4-
• aggressive

Plasma cell neoplasms is a group of diseases composed of immunoglobulin-secreting cells in the absence of neoplastic B lymphs.

• True

• False