WEEK 2 DIAGNOSTIC TEST

Write 3 points from the reading material you most remember

False positive beta-d-glucan (BDG) can occur in the following setting, except:

• patient treated with amoxycillin-clavulanic acid

• hematological malignancy

• hemodialysis

• dengue patient receiving normal saline fluid replacement

BDG can be used as an adjunct in the diagnosis of invasive fungal infection. Which one of the following statement is incorrect?

• It is positive in mucormycosis

• it is negative in cryptococcosis

• can be used as surveillance for invasive fungal infection in high risk group, (eg hematologic malignancy undergoing chemotherapy)

• false positive in pseudomonas bacteremia

Choose correct statement regarding galactomannan (GM) (can choose more than 1)

• It is gold standard test for invasive aspergillosis

• Good positive and negative predictive value in hematologic neutropenic patients

• Reliable test for invasive aspergillosis in non-neutropenic population

• GM index can be used to monitor treatment response

Fungal infections on the skin are likely to be analyzed with the use of a

• culture swab

• blood culture

• blood sampling

• stained slide mount

Choose correct statement for fungal serological test (can choose more than one)

• positive galactomannan precedes symptoms of the invasive aspergillosis

• histoplasmosis antigenemia is more sensitive than the antigenuria

• The presence of histoplasma antibodies can be used to diagnose recent infection

• An infection with Trichosporon sp can cause false positive latex agglutination test for cryptococcus