Enzymes

Primary pathway metabolizing enzyme of Bupropion?

• 2B6

• 3A4

• 2D6

• 2C9

• 2C19

Primary pathway metabolizing enzyme of Diphenhydramine?

• 2B6

• 3A4

• 2D6

• 2C9

• 2C19

Primary pathway metabolizing enzyme of Sitagliptin?

• 2B6

• 3A4

• 2D6

• 2C9

• 2C8

Primary pathway metabolizing enzyme of Glipizide?

• 2B6

• 3A4

• 2D6

• 2C9

• 2C19

Metformin is metabolized by OCT1, OCT2.

• True

• False

Which primary pathway metabolizing enzyme is common to all Proton Pump Inhibitors?

• 2B6

• 3A4

• 2D6

• 2C9

• 2C19

Which of the following PPIs are also metabolized by both CYP2C19 and CYP3A4?

• Lansoprazole

• Pantoprazole

• Omeprazole

• Esomeprazole

Codeine, Tramadol, Risperidone, Tamoxifen, Tamsulosin are metabolized by which enzyme(s)?

• 2D6

• 3A4

• 2B6

• 2C19

• 2C9

Alprazolam, Clonazepam, Carbamazepine. Clindamycin, Hydrocodone, and Oxycodone are metabolized by which enzyme(s)?

• 2D6

• 3A4

• 2B6

• 2C19

• 2C9

Which of the following PPIs are weak inhibitors CYP2C19 and OAT1/3?

• Lansoprazole

• Pantoprazole

• Omeprazole

• Esomeprazole