Platelet disorders

The gray platelet syndrome is abnormality of:

• Dense granules components of platelets

• toxic platelets

• impaired platelet aggregation

• aspirin like defects

In von Willebrand’s disease, an absent or abnormal form of the vWf results in impaired

• Platelet adhesion

• platelet aggregation

• platelet secretion

• platelet release

Which of the following platelet function is inhibited by the aspirin?

• Platelet adhesion

• Platelet Aggregation

• Platelet secretion

• Platelet release

The result of postsplenectomy, regardless of the reason

• thrombocytopenia

• thrombasthenia

• thrombocytosis

• thrombosis

The term that corresponds with the lay term term bruise

• petechiae

• ecchymosis

• hematoma

• purpura

Aspirin prevents platelet aggregation by inhibiting the action of which enzyme?

• Prostacyclin synthetase

• Thromboxane A2 synthetase

• Cyclo-oxygenase

• Phospholipase

Normal platelet adhesion depends upon:

• Fibrinogen

• Glycoprotein Ib

• Glycoprotein IIb, IIIa complex

• Calcium

Hereditary hemorrhagic telangiectasia is a disorder of:

• platelets

• clotting factors

• fibrinolysis

• connective tissue

Bernard–Soulier syndrome is associated with:

• Abnormal platelet aggregation to ADP

• Thrombocytopenia and giant platelets

• Decreased factor VIII assay

• Decreased bleeding time

Which of the following test results is normal in a patient with classic von Willebrand’s disease?

• bleeding time

• Activated partial thromboplastin time

• Platelet count

• Factor VIII:C and von Willebrand’s factor

  (VWF) levels