Party Quiz

A 25-year-old woman has a long history of depressive symptoms accompanied by body aches and pain secondary to a car accident. Which of the following drugs might be useful in this patient?

• Fluoxetine

• Sertraline

• Phenelzine

• Duloxetine

A 51-year-old woman with symptoms of major depression also has angle-closure glaucoma. Which antidepressant should be avoided in this patient?

• Amitriptyline

• Bupropion

• Mirtazapine

• Fluvoxamine

Which antidepressant has, as its two proposed principal mechanisms of action, 5-HT1a receptor partial agonism and 5-HT reuptake inhibition?

• Fluoxetine

• Aripiprazole

• Maprotiline

• Vilazodone

Which antidepressant is the most sedating?

• Bupropion

• Duloxetine

• Doxepin

• Venlafaxine

Which mood stabilizer is completely renally eliminated and may be beneficial for patients with hepatic impairment?

• Valproic acid

• Carbamazepine

• Lithium

• Risperidone

Which antidepressant has, as its two principal mechanisms of action, 5-HT2A receptor antagonism and α2 receptor antagonism?

• Fluoxetine

• Doxepin

• Maprotiline

• Mirtazapine

Which mood-stabilizing agent is most likely to decrease the thyroid function?

• Carbamazepine

• Lithium

• Valproic acid

• Chlorpromazine

Which antidepressant agent has significant α1 receptor antagonism and, thus, is a poor choice in an elderly female with depressive symptoms due to a higher risk of falls related to orthostatic hypotension?

• Venlafaxine

• Bupropion

• Escitalopram

• Amitriptyline

A 55-year-old teacher was diagnosed with depression. After 6 weeks of therapy with fluoxetine, his symptoms improved, but he complains of sexual dysfunction. Which of the following drugs might be useful for management of depression in this patient?

• Sertraline

• Citalopram

• Mirtazapine

• Lithium