6th HEMA

It is the planned and systematic activities used to provide adequate confidence that requirements for quality will be met.

• Quality

• Quality assurance

• Quality management

• None of the choices

Select the rule/s which indicate/s a Systematic Error:

• 1:3s

• 2:2s

• 4:1s

• None of the choices

K.B., a 15-year-old male, came in for admission due to prolonged bleeding of his left knee after falling from the 2 flights of stairs trying to do a viral tiktok dance. On physical exam, he has a 5 cm laceration on his left knee with multiple hematoma. He also had hemarthrosis on his right knee. The rest are unremarkable. He was a relatively healthy boy growing up. No previous hospitalizations or infections, but was noted to have frequent gum bleeding. His mother has history of easy bruising. He claims to have not met his dad and was only raised by his mother. Labs: APTT- 90 secs (prolonged) PT- 11 secs (Normal) Bleeding time- 4 mins (Normal) Platelet count- 120,000/mm3 (decreased) Fibrinogen- 345 mg/dL (Normal) Clotting factor assay: FVIII- 80% activity FIX4% activity (decreased) Peripheral blood smear: Thrombocytopenia with normal sized platelets. What is the diagnosis for this case?

• Wiskott- Aldrich Syndrome

• Scurvy

• Disseminated intravascular coagulation

• Hemophilia B

Which is the characteristic triad of Wiskott- Aldrich syndrome?

• Eczema, atopic dermatitis, thrombocytopenia with small platelets

• Eczema, recurrent infections, thrombocytopenia with small platelets

• Eczema, recurrent infections, thrombocytosis with small platelets

• Atopic dermatitis, recurrent infections, thrombosis with small platelets

Select the statement/s which is/are TRUE regarding the Advantages of the different methods of Endpoint detection:

• In mechanical endpoint detection, there is no interference from lipemia or icterus.

• With photo-optical method, there is an ability to observe graph of clot formation.

• For chromogenic method, there is an ability to measure proteins that do not clot.

• None of the choices

This method of endpoint detection quantifies plasma protein based on the specific reaction of the protein being measured with highly specific antisera.

• Nephelometric

• Chromogenic

• Amidolytic

• Immunologic

Ideal temperature for coagulation studies procedures is:

• 36C

• 37C

• 38C

• None of the choices

How much is the maximum dose of Vitamin C for adults?

• <2000 mg/day

• <2 mg/ day

• <1000 mg/day

• <1 mg/day

The following applies to Congenital Afibrinogenemia:

1- Bleeds more frequently than hemophilia

2- Autosomal recessive disorder

3- Hemarthrosis is always seen

4- Marked prolongation of PT and APT

• 1, 3 only

• 2, 4 only

• 1, 2, 3 only

• All of the above

This method measures how much a chemical substance absorbs light by measuring the intensity of light as a beam of light passes through sample solution:

• Spectrophotometry

• Fluorometry

• Nephelometry

• None of the choices