Micro Final Practice

What are 3 signs of overt iron deficiency?

• ADHD

• Fatigue

• Infection prone

• Vomiting

• Diarrhea

What are three signs of overt iron deficiency? What are three different biochemical functions of iron that are impaired during these signs of deficiency?

Answer explanation

1. ADHD -- dopamine signaling -- reduced brain function

2. Fatigue -- ETC -> mitochondria

3. Infection prone -- immune function

One overt sign of iron deficiency is ADHD. Why is that?

• Reduced serotonin signaling leads to reduced brain function

• Lack of oxygen for ETC leads to fatigue and impaired brain signaling

• Reduced dopamine signaling leads to reduced brain function

One overt sign of iron deficiency is fatigue. Why is that? What biochemical functions of iron are impaired during this sign?

Answer explanation

When iron deficient, there is a lack of oxygen for the final carrier in the ETC. This leads to reduced energy.

What are two reasons why the RDA for iron in lactating women is lower than for adult women and lower than for pregnancy?

Based on what you know about iron needs in adult women, why does the RDA for iron in older women (50+) decrease compared to adult women?

Name a genetic disorder that results in excess iron absorption in the intestine.

What is a biomarker that is commonly elevated in people with hemochromatosis?

What are three symptoms/physiological signs of hemochromatosis?

Answer explanation

1. Browning, rusting of skin

2. Pancreas & liver damage

3. Joint problems

What are three symptoms or physiological signs of hemochromatosis?

• Browning of the skin

• Yellowing of the skin

• Pancreas & liver damage

• Joint problems