Uve Hour (May 5)

Characteristic clinical findings in acute retinal necrosis (ARN) include the following (check all that apply):

• circumferential or confluent retinitis

• retinal vascular sheathing and/or occlusion

• no or very minimal vitritis

• disc edema

ARN is most commonly caused by which virus/es? (Check all that apply.)

• EBV

• VZV

• CMV

• HSV

Induction treatment of ARN (Check all possible answers)

• IV acyclovir (10mg/kg TID)

• Oral valacyclovir (2000 mg TID)

• Oral valgancyclovir (900 mg BID)

• Intravitreal foscarnet or gancyclovir

  (1-2x/wk)

Maintenance treatment of ARN (Check all that apply).

• Oral valacyclovir (1000 mg TID)

• Oral acyclovir (800 mg 5x/day)

• Intravitreal foscarnet or gancyclovir every month

• Treatment is given for a period of 6-12 months

Which is true of prophylaxis treatment for ARN?

• Oral valacyclovir (1000 mg/day) for 6-12 months

• Oral valacyclovir (1000 mg/day) until immune function is recovered

• Oral valacyclovir (1000 mg/day) for life

• Oral valacyclovir (1000 mg/day) for 3 months after induction phase

Oral corticosteroids are contraindicated in the treatment of ARN.

• True

• False

Measures proven to decrease the incidence of retinal detachment in ARN (Check all that apply).

• Early initiation of antiviral therapy

• Prophylactic laser

• Prophylactive vitrectomy

• Use of corticosteroids