Thalidomide

In what country was Thalidomide firstly distributed?

• The UK

• Germany

• France

• The USA

What was Thalidomide used for?

• Morning sickness

• Stomach ache

• Shortness of Breath

• High blood pressure in pregnant women

This picture describes that Thalidomide....

• Is a molecule that likes to look at itself in the mirror.

• is an optical isomer.

• Is superimposable

• has two chiral centers.

What is phocomelia?

• A condition that disrupts our vision.

• The lack of oxygen and metal ions in our blood.

• A type of toxicity caused by drugs.

• A type of congenital malformation.

A ______ is an agent that causes malformations in fetuses.

• coordination compound

• teratogen

• carcinogen

• mutagen

Which atom(s) in the molecule is/are a chiral center?

• 1 & 2

• only 3

• all except 4

• 3 & 2

What it the most common chiral center in organic chemistry?

• carbon

• nitrogen

• oxygen

• triple carbon bonds

Which enantiomer is the one which caused birth defects on babies?

• 
• 

Why was isolating only one entiomer of thalidomide a failure?

• Because its too expensive to separate them.

• Racemic mixtures are the only way to administer medicines.

• An enzyme in the liver automatically converts it to the unsafe enantiomer.

• Because our stomach acid destroys it.

Thalidomide is still used as _______, despite its controversy.

• a drug to treat cancer

• an antiviral drug

• an example of what not to do

• a drug for veterinary purposes