Lesson 10 - DNA Replication

Which pair of nucleotide components is directly bonded by phosphodiester linkages in a DNA polymer?

• deoxyribose and phosphate

• nitrogenous base and deoxyribose

• phosphate and purines

• deoxyribose and pyrimidines

Complementary base pairing enables _____.

• directed replication of a double helix

• formation of a double helix composed of two identical strands

• each purine to align with its corresponding purine

• any purine to align with any pyrimidine

The complementary strand of the DNA sequence 5’-CGATTG-3’ is _____.

• 3’-GCTAAG-5’

• 3’- CGATTG -5’

• 5’- GCTAAG -3’

• 5’-CGATTG-3’

The association between two strands stabilizing a DNA double helix depends upon _____.

• hydrogen bonds between purine-pyrimindine base pairs

• hydrogen bonds between purine-purine base pairs

• ionic bonds between the sugar and phosphate groups

• covalent bonds between the sugar and phosphate groups.

In living cells, heritable information is stored in _____.

• DNA

• RNA

• both nucleic acids

• alternate base pairing

Chargaff’s observation that DNA contained equal amounts of the nitrogenous bases cytosine and guanine and equal amounts of the nitrogenous bases adenine and thymine led Watson and Crick to the conclusion that DNA is composed of two strands, _____.

• one containing purines and the other containing a complementary set of pyrimidines

• with each strand possessing identical bases

• with bases aligned in complementary pairs across the two strands

• each strand containing alternating purine and pyrimidine bases

Rosalind Franklin’s work with X-ray diffraction patterns of DNA molecules helped _____.

• Weismann identify chromosomes as the carriers of heredity

• Watson and Crick develop the DNA double helix model

• Meselson and Stahl devise an experiment to test replication models

• Griffith develop his hypothesis about DNA as the transforming principle

By purifying DNA from S-strain bacteria, Avery, MacLeod, and McCarty _____.

• showed that proteins could be the agent of heredity

• demonstrated that DNA was not the transformation molecule

• verified the DNA double helix model suggested by Watson and Crick

• demonstrated DNA could transform bacteria

Hershey and Chase worked with bacteriophage viruses to determine what hereditary material was passed into bacteria during infection. These researchers demonstrated _____.

• the structure of DNA

• the concentration of nitrogenous bases in a bacterial cell

• that DNA directed synthesis of proteins

• how DNA was replicated

During semiconservative DNA replication, _____.

• both original strands act as templates (parental strands)

• only one DNA strand acts as a template

• the new daughter strands bind to form the new helical DNA

• most base pairing is conserved during replication