Ristova Assessments

Where does process of blood formation takes place?

• Bone
• Myeloid lineage
• Lymphoid lineage
• Bone marrow

Staging of NHL- Ann arbor staging system- Two or more Lymph nodes regions above and below the diaphragm are calles

• Stage-1
• Stage-2
• Stage 3
• Stage 4

What is dose of Rituximab in DLBCL

• 350 mg/m2
• 500 mg/m2
• 375 mg/m2
• None of Above

What is dose of rituximab in CLL

• 350 mg/m2 in first cycle followed with 500 mg/m2
• 500 mg/m2 in first cycle followed with 400 mg/m2
• 375 mg/m2 in first cycle followed with 500 mg/m2
• All the above

What is infusion rate for Rituximab in first cycle

• 150 mg/hr with escalation of 100 mg/hr increment every 30 mins maximum of 400 mg/hr
• *50 mg/hr with escalation of 50 mg/hr increment every 30 mins maximum of 400 mg/hr
• 50 mg/hr with escalation of 100 mg/hr increment every 30 mins maximum of 400 mg/hr
• 100 mg/hr with escalation of 100 mg/hr increment every 30 mins maximum of 400 mg/hr

Rituximab Dilution done in

• 0.9% sodium chloride solution
• 5% dextrose solution
• Water for Injection
• All of the above
• Option A & B

What is Mechanism of Action of Rituximab

• Complement dependent cytotoxicity CDC
• Anti body dependent Cellular cytotoxicity ADCC
• Apoptosis
• All of the above
• Both A & B

What is premedication given before Rituximab infusion

• Cyclophosphamide
• Doxorubicin
• Prednisone
• Vincristine
• All of the above

Rituximab is

• Anti CD 19
• Anti CD 20
• Anti CD 52
• Anti CD 10

What are approved indication for Rituximab

• NHL
• CLL
• Rheumatoid Arthritis
• Wengner Granulomatis & Microscopic Polyangitis
• All of the above