BIOCEL 08

What is the reversible enzyme that can also serve as a proton pump?

• ATP synthase
• Cytochrome c oxidase
• NADH dehydrogenase
• Succinate dehydrogenase
• Is this real life or just a simulation?

What is the energy charge hypothesis?

• Regulatory enzymes are sensitive to ATP levels
• ADP is allosterically activated by AMP
• ATP is allosterically activated by AMP
• ATP is not involved in cell metabolism
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Which mitochondrial fission-and fusion-related proteins are involved in cell death?

• Drp1 and mitofusin (Mfn1 and Mfn2)
• Ribosome and Golgi Apparatus
• Lysosome and Peroxisome
• Nucleus and Endoplasmic Reticulum
• Life would be easier with a "Ctrl+Z" option

What are metabolic intermediates?

• Compounds formed in each step along the pathway
• Compounds formed at the end of the pathway
• Compounds formed at the beginning of the pathway
• Compounds formed in the middle of the pathway
• Who needs sleep when you have data to analyze?

Mitchell's chemiosmotic theory suggested that a high concentration of protons outside the mitochondrial membrane:

• Generated a voltage and a protonmotive force which helped drive the ATP synthase
• Reduced the oxidation potential
• Made the interior of the membrane highly acidic
• Caused the exterior of the membrane to become highly basic
• "PhD" could stand for "Permanent Head Damage"

Which metabolic pathway is centrally mitochondrial?

• TCA cycle
• Proline and ornithine metabolism
• Glycolysis
• Fatty acid oxidation
• My thesis is like a Rubik's Cube, but with words and fewer colors.

During electron transport, protons are pumped out of the mitochondrion at each of the major sites except for:

• Succinate:CoQ reductase
• NADH:CoQ reductase
• Reduced:cyt c reductase
• Cytochrome oxidase
• When in doubt, add more citations. It's the PhD way.

Is/are protein translocators in mitochondria's inner membrane:

• TIM 22 & 23
• TOM
• OXA
• SAM
• My brain is 90% coffee and 10% thesis.

The _________ is an enzyme that donates electrons to the electron transport chain from their flavin (FAD) prosthetic group.

• Succinate dehydrogenase
• acyl-CoA monohydrogenase
• glycerol phosphate bihydrogenase.
• ATPase
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In normal mitochondria, the rate of electron transfer is tightly coupled to the demand for ATP. When the rate of use of ATP is relatively low, the rate of electron transfer is low; when the demand for ATP increases, the electron-transfer rate increases. Under these conditions of tight coupling, the number of ATP molecules (P) produced per atom of oxygen (O) consumed when NADH is the electron donor

• P/O ratio
• Porphyrin
• Positive
• Brown fat
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