Acne

Which of the following is a light. yellow, oily substance consisting of triglycerides, free fatty acids, and cholesterol?

• Sebum

• Keratin

• Pus

• Sweat

Answer explanation

Sebum is produced by the sebaceous glands. This oily matter lubricates the skin and hair. An overproduction or blockage of the release of sebum can contribute to acne.

Which of the following should be tried FIRST for mild acne? (Select all that apply)

• Benzoyl peroxide

• Topical Retinoids

• Oral retinoids

• Oral antibiotics

Answer explanation

The guidelines state that BP and topical retinoids are pretty equivalent as fas as efficacy and safety. Both can be considered "first line". Dr. Potter prefers BP because of its accessibility, affordability, and unique MOA. Patient preferences and tolerability should be taken into consideration.

What is the main risk associated with using oral antibiotics as monotheraoy?

• Bacterial resistance

• Therapy failure

• Systemic side effects

• Cost

Answer explanation

The main risk is bacterial resistance. This is why we will not use them as monotherapy or as maintenance chronic therapy. Oral antibiotics (compared to topical antibiotics) do come with a higher risk of systemic side effects, but these will occur regardless of whether they're taken as monotherapy or combined with other medications.

Which topical agent would not be suitable for children < 12 because of an increased risk of Reye's syndrome?

• Benzoyl peroxide

• Salicylic acid

• Dapsone

• Topical retinoids

Answer explanation

"Use of salicylates in children with varicella infection or influenza-like illnesses is associated with an increased risk of developing Reye’s syndrome; A rare but serious condition that causes confusion, swelling in the brain, and liver damage."

Which of the following medications for acne is considered safe in pregnancy?

• Benzoyl peroxide

• Topical retinoids

• Azelaic acid

• Doxycycline

Answer explanation

All of the other options are NOT considered safe in pregnancy.

Which one of the following topical medications for acne would require a prescription regardless of strength?

• Dapsone

• Salicylic acid

• Benzoyl peroxide

• Adapalene

Answer explanation

Both strengths of Dapsone (Aczone) are only available with a prescription. All of the other options are available in some form without a prescription, but higher strengths may require a prescription.