COMPLEMENT SYSTEM

2nd most abundant complement protein

• C1

• C4

• C5

• C3

Antibody-independent of activating complement proteins

• Lectin Pathway

• Complement

• Classical Pathway

• Alternative PAthway

Plays a major part in amplifying the inflammatory response to destroy a clear foreign antigens.

• Alternative pathway

• Classical pathway

• Lectin binding pathway

• Complement

Complement component acting as chemotactic factor

• C5a

• C2a

• C3b

• C4b

C3 convertase is

• C4b2b

• C4b2a

• C4b3b

• C4a2b

small peptide that causes increased vascular permeability, contraction of smooth muscle, & release of histamine from basophils and mast cell.

• Opsonin

• Anaphylatoxin

• Chemotaxis

• None of the above

Principal soluble regulator

• Factor H

• DAF

• C4BP

• S Protein

Which of the complement receptor activate phagocytosis by binding to C3b & C4b coated particles?

• CR1

• CR2

• CR3

• CR4

Recognize Fc region of two adjacent antibody molecules

• C1q

• C1s

• C3b

• C9

Lupus like syndrome

• C1

• C1-INH

• C2

• 2 of the above.