Quiz about Biochem: Citric Acid Cycle

Question 1

Only a small amount of energy is captured in glycolysis.

Accepted Answer

True

Answer

False

Question 2

Glycolysis can occur in both aerobic and anaerobic environment.

Accepted Answer

True

Answer

False

Question 3

Which has a higher delta G?

Accepted Answer

full oxidation

Answer

glycolysis

Question 4

Glycolysis is NOT thermodynamically favorable.

Accepted Answer

False

Answer

True

Question 5

Oxygen is required for glycolysis.

Accepted Answer

False

Answer

True

Question 6

Oxygen is required for citric acid cycle.

Accepted Answer

True

Answer

False

Question 7

Which organell is the major site for aerobic energy production in eukaryotic cells?

Accepted Answer

mitochondria

Answer

Ribosome

Answer

Nucleus

Answer

smooth ER

Question 8

Where are mitochondria most abundant? (two answers)

Accepted Answer

muscle cells

Accepted Answer

liver cells

Answer

pancreatic cells

Answer

kidney cells

Question 9

How do RBC's get their energy?

Accepted Answer

glycolysis

Answer

Citric acid cycle

Answer

both glycolysis and citric acid cycle

Question 10

Red blood cells have many mitochondria.

Accepted Answer

False

Answer

True

Question 11

Where are the enzymes for the citric acid cycle located?

Accepted Answer

matrix

Answer

inner mitochondrial membrane

Answer

outer mitochondrial membrane

Question 12

Which is MORE selective?

Accepted Answer

inner mitochondrial membrane

Answer

outer mitochondrial membrane

Question 13

What serves as a link to the electron transport chain and oxidative phosphorylation?

Accepted Answer

citric acid cycle

Answer

glycolysis

Answer

gluconeogenesis

Answer

glycogenolysis

Question 14

The citric acid cycle generates coenzymes.

Accepted Answer

True

Answer

False

Question 15

What are two important enzymes generated by the TCA cycle?

Accepted Answer

NADH

Accepted Answer

FADH2

Answer

NADPH

Question 16

What is the role of NADH and FADH2?

Accepted Answer

to pass their electrons to oxygen to generate energy for the cell

Answer

to generate lactic acid

Answer

to gain electrons from the TCA cycle

Question 17

The more negative the electron potential, the more readily they give up electrons.

Accepted Answer

True

Answer

False

Question 18

Which is a better electron DONOR?

Accepted Answer

NADH

Answer

FADH2

Question 19

What can feed into the TCA cycle as starting material?

Accepted Answer

fatty acids

Accepted Answer

amino acids

Accepted Answer

glucose

Answer

NADH

Question 20

What is the starting material for the TCA?

Accepted Answer

Acetyl CoA

Answer

phosphate

Answer

NADH

Answer

ATP

Question 21

What is the product of TCA cycle?

Accepted Answer

NADH and FADH2

Accepted Answer

2 CO2

Accepted Answer

1 ATP

Answer

lactic acid

Question 22

Where do NADH and FADH2 go after they are formed in the TCA cycle?

Accepted Answer

ETC

Answer

into the matrix

Answer

ATP synthase

Question 23

Where does the electron transport chain take place?

Accepted Answer

in the inner mitochondrial membrane

Answer

in the outer mitochondrial membrane

Answer

in the matrix

Question 24

Which kind of amino acids can be turned into Acetyl-CoA and feed into the TCA cycle?

Accepted Answer

ketogenic amino acids

Answer

glucogenic amino acids

Question 25

Where can gllucogenic AA be used?

Accepted Answer

in gluconeogenesis

Answer

to make Acetyl CoA

Answer

in the TCA cycle

Question 26

The citric acid cycle ONLY occurs in the mitochondrial matrix.

Accepted Answer

True

Answer

False

Question 27

Where does glycolysis occur?

Accepted Answer

cytoplasm

Answer

mitochondria

Answer

in the nucleus

Question 28

Where is succinate dehydrogenase located?

Accepted Answer

the inner membrane of the mitochondria

Answer

the mitochondrial matrix

Answer

the outer membrane of the mitochondria

Question 29

Where does pyruvate come from?

Accepted Answer

glycolysis in the cytoplasm

Answer

the matrix

Answer

the nucleus

Question 30

Pyruvate cannot cross the inner mitochondrial membrane.

Accepted Answer

False

Answer

True

Question 31

Where does oxidative phosphorylation occur?

Accepted Answer

in the inner membrane

Answer

in the cytoplasm

Answer

in the matrix

Question 32

Where does the ETC occur?

Accepted Answer

inner membrane

Answer

cytoplasm

Answer

outer membrane

Answer

matrix

Question 33

What must happen to pyruvate before entering the citric acid cycle?

Accepted Answer

it must be converted to Acetyl CoA

Answer

it must be phosphorylated

Answer

it must be degredated

Answer

nothing, it enters the TCA directly

Question 34

How does pyruvate enter the mitochondrial matrix?

Accepted Answer

through a transporter

Answer

gets converted to malate

Answer

passive diffusion

Question 35

The decarboxylation of pyruvate to make acetyl CoA is irreversible.

Accepted Answer

True

Answer

False

Question 36

What does the dehydrogenase complex do and how many enzymes make this up?

Accepted Answer

removes carboxy group and adds S-CoA; 3

Answer

adds phosphate group;2

Answer

removes hydrogen; 5

Question 37

How many coenzymes are required for the pyruvate dehydrogenase complex?

Accepted Answer

5

Answer

1

Answer

2

Answer

3

Question 38

TPP,lipoyllysine, and FAD are all....

Accepted Answer

prosthetic groups

Answer

coenzymes

Answer

cofactors

Answer

ions

Question 39

NAD+ and CoA-SH are co-substrates.

Accepted Answer

True

Answer

False

Question 40

What are the products of the pyruvate dehydrogenase complex?

Accepted Answer

CO2

Accepted Answer

Acetyl-CoA

Accepted Answer

NADH

Answer

FADH2

Question 41

How many NADH's are made outside of the TCA cycle?

Accepted Answer

1NADH

Answer

2 NADH

Answer

3 NADH

Question 42

Where is the NADH made outside of the citric acid cycle?

Accepted Answer

in the conversion of pyruvate to Acetyl-CoA

Answer

in the conversion of citrate to isocitrate

Answer

in the conversion of fumarate to malate

Question 43

Acetyl-CoA is a low energy molecule.

Accepted Answer

False

Answer

True

Question 44

Pyruvate dehydrogenase complex is only made up of one enzyme.

Accepted Answer

False

Answer

True

Question 45

Pyruvate dehydrogenase is

Accepted Answer

enzyme 1

Answer

enzyme 2

Answer

enzyme 3

Question 46

dihydrolipoyl transacetylase is

Accepted Answer

enzyme 2

Answer

enzyme 1

Answer

enzyme 3

Question 47

dihydrolipoyl dehydrogenaase is

Accepted Answer

enzyme 3

Answer

enzyme 1

Answer

enzyme 2

Question 48

The short distance between catalytic sites is an advantage of a multienzyme complex.

Accepted Answer

True

Answer

False

Question 49

Why is it important for the enzyme complex to have short distances between catalytic sites?

Accepted Answer

to minimize side reactions

Answer

to work slower

Answer

the maximize side reactions

Question 50

Which reaction has a C-C bond formation?

Accepted Answer

Condensation of acetyl-CoA and oxaloacetate

Answer

Isomerization by dehydration

Answer

oxidative decarboxylations

Question 51

Condensation of acetyl-CoA and oxaloacetate (1st step of CAC) is the only reaction with C-C bond formation.

Accepted Answer

True

Answer

False

Question 52

Step 1 of CAC where acetyl Co-A and oxaloacetate go through condensation reaction is

Accepted Answer

Favorable

Accepted Answer

irreversible

Answer

unfavorable

Answer

reversible

Question 53

What must be present for the first step of CAC?

Accepted Answer

oxaloacetate

Answer

oxygen

Answer

citrate

Answer

ATP

Question 54

Step 2 of CAC is the dehydration and rehydration of citrate.

Accepted Answer

True

Answer

False

Question 55

What enzyme catalyzes the dehydration and rehydration of citrate?

Accepted Answer

aconitase

Answer

citrate synthase

Answer

isocitrate dehydrogenase

Question 56

Citrate is a poor substrate for oxidation but gets turned into isocitrate that is a good substance for oxidation.

Accepted Answer

True

Answer

False

Question 57

They dehydration and rehydration of citrate is

Accepted Answer

reversible

Accepted Answer

unfavorable

Answer

favorable

Answer

irreversible

Question 58

What allows the dehydration and rehydration of citrate to pull forward even though it is thermodynamically unfavorable?

Accepted Answer

product concentration is kept low

Answer

substrate concentration is kept low

Answer

product concentration is kept high

Question 59

Step 3 of CAC What is the intermediate between isocitrate and a-ketoglutarate?

Accepted Answer

oxalosuccinate

Answer

not this one

Question 60

The first NADH produced within the CAC is the oxidative decarboxylation of isocitrate.

Accepted Answer

True

Answer

False

Question 61

The formation of a-ketoglutarate from isocitrate is

Accepted Answer

favorable

Accepted Answer

irreversible

Answer

unfavorable

Answer

reversible

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