Genetic Factors in Schizophrenia A01

What is the estimated heritability of schizophrenia?

• 39%

• 59%

• 79%

• 99%

How many genes have been linked to schizophrenia?

• 100

• 300

• 700

• 1,000

What can cause spontaneous changes in the DNA code?

• Environmental factors

• Cell division errors

• Both A and B

• None of the above

Which syndrome is caused by the deletion of genes on chromosome 22?

• Down Syndrome

• Turner Syndrome

• DiGeorge Syndrome

• Klinefelter Syndrome

Which gene is linked to the presence of schizophrenia in DiGeorge Syndrome?

• COMT gene

• DISC1 gene

• GABA gene

• Glutamate gene

People with an abnormality in which gene are more likely to develop schizophrenia?

• COMT gene

• DISC1 gene

• GABA gene

• Glutamate gene

What does the DISC1 gene code for?

• Dopamine

• GABA

• Glutamate

• Serotonin

Do genes cause schizophrenia or create a vulnerability for it?

• Genes cause schizophrenia

• Genes create a vulnerability

• Both A and B

• None of the above

What is considered as 'stress' in the diathesis-stress model of schizophrenia?

• Psychological factors

• Harsh parenting

• Cannabis use

• All of the above

What is the risk of developing schizophrenia due to cannabis use?

• 1.5 times

• 3 times

• 5 times

• 7 times