275 Pharmacology Ch 4&5

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• x

• y

Which one of these is NOT one of the four basic pharmacokinetic processes:

• Absorption
  

• Distribution

• Metabolism (biotransformation)
  

• Excretion
  

• All of these are correct

What is the role of absorption in pharmacokinetics?

• Absorption is the process by which a drug is eliminated from the body.
• Absorption is the process by which a drug is metabolized in the liver.
• Absorption is the process by which a drug is excreted through the kidneys.
• Absorption is the movement of drugs from their site of administration into the bloodstream.

Which pharmacokinetic process involves the alteration of a drug's structure by enzymes?

• absorption
• metabolism
• excretion
• distribution

What is the definition of excretion in pharmacokinetics?

• Transformation of drugs in the body
• Elimination of drugs or their metabolites from the body
• Distribution of drugs within the body
• Absorption of drugs into the body

5. What term is used to describe the combination of metabolism and excretion in pharmacokinetics?

• elimination
• biotransformation
• distribution
• absorption

In pharmacokinetics, what does the term "distribution" refer to?

• The movement of drugs from the blood to the interstitial space of tissues.

• Absorption of a drug into the bloodstream
• Elimination of a drug from the body
• Metabolism of a drug in the body

What are the root words of Pharmacokinetics?

• pharmakon (drug or poison) and kinesis (motion)

• pharmaco, dynamics
• pharmaco, movement
• pharmaco, action

Name 3 ways a drug can cross a cell membrane:

• passage through channels or pores

• passage with the aid of a transport system

• direct penetration of the membrane itself

Answer explanation

Of the three, direct penetration of the membrane is most common.

What important protein transports drugs OUT of cells?

• ATP-binding cassette transporter
• Drug efflux pump
• Drug influx transporter
• P-glycoprotein