Granules Pop Quiz

Granules are

• Agglomerated of liquid substances

• Agglomerated of small powder particles

• Agglomerated of liquid medications

• Agglomerated of gelatin sheet

What are the typical size range for pharmaceutical granules?

• 1-2 nm

• 4.75 - 1.7nm

• 20-30nm

• 100-200 um

What is the primary advantage of using wet granulation methods in pharmaceuticals?

• Uniformity of particle size

• Moisture resistance

• Decrease manufacturing time

• Enhanced tablet dissolution

What is the role of fluidized bed granulation method?

• Binding granules with adhesive

• Creating wet moisture

• Forming granule from dispersed particle

• Drying granules

Why granules are favorable over powders in pharmacuetical manufacturing?

• Enhanced aroma

• Better choice of colours

• Faster dissolution

• Improved flow properties

Which method is used to form granules in dry granulation?

• Applying pressure

• Using liquid excipients

• Crushing and sizing

• Wetting the mixture

Shelf life of granules is about 4 weeks

• True

• False

Which of the following is NOT the container for bulk granules?

• Plain glass

• Plastics jars with close fitting

• Amber closure container

• All of the above

The following is an example of granulated commercial product EXCEPT:

• Cloxacillin

• Terbinafine

• Montelukast

• Senokot

Patients should dissolve and mix granules with water before taking them orally

• True

• False