Myasthenia Gravis

What type of nicotinic acetylcholine receptor is found at the Neuromuscular Junction (NMJ)?

Which of the following autoantibodies is most classically seen in myasthenia gravis? Antibodies against...

• nicotinic acetylcholine receptor

• muscarinic acetylcholine receptor

• voltage-gated sodium channels

• presynaptic voltage-gated calcium channels

Which finding is most consistent with myasthenia gravis?

• muscle weakness which improves with exercise

• negative edrophonium test

• fatigable muscle weakness which worsens with exercise, but improves with rest

• recent onset of symmetric muscle paralysis and hyporeflexia

Which is NOT a classic finding in myasthenia gravis?

• fatigable proximal muscle weakness

• ptosis

• dysphagia

• dyspnea

• abnormal deep tendon reflexes

Which of the following diseases is NOT associated with myasthenia gravis?

• Hashimoto's thyroiditis

• Rheumatoid arthritis

• Systemic lupus erythematosus

• Thymoma

• Lung tumor

Myasthenic crisis results in life-threatening _______ failure.