Chromosome structure and number

Which is/ are the chromosomal mutations?

• Deletion

• Duplication

• Inversions

• Translocations

Chromosome are NOT defined by ________

• Location of centromere

• Banding pattern

• Size

• Number of genes

Chi Du Chat Syndrome is an example of _________ mutation.

• Duplication

• Deletion

• Translocations

• Inversions

This mutation type is hypothesized to be a major sources of new genes in the evolution

• Deletion

• Translocation

• Duplication

• Inversion

Choose TWO types of Inversion mutation.

• Dicentric

• Paracentric

• Acentric

• Pericentric

Familial Down Syndrome is an example of 14/21 translocation mutation.

• True

• False

What is a chance for a Down Syndrome mother to have a normal child? (assuming the father is normal)

• 50% chance

• 100% chance

• 25% chance

• 75% chance

Common Fragile Sites (CFS) can easily be found in human chromosomes.

• True

• False

Which one of the designated below is a wild type phenotype?

• B+/B

• B+/B+

• B/B

• B-/B-

The chromosome segments breaks at two points, turned 180 degree within chromosome and reinsert to the chromosome.

• Deletion

• Duplication

• Inversion

• Translocation