Replication in Eukaryotes Quiz

What are the differences between prokaryotic & eukaryotic DNA?

• Number of origins of replication

• Presence of telomerase

• Type of DNA polymerases

• Length of DNA strands

Which enzyme is responsible for unwinding and separation of the two DNA strands in eukaryotic DNA replication?

• FEN1

• RPA

• MCM

• ORC

Which DNA polymerase is responsible for synthesis of the lagging strand in eukaryotic DNA replication?

• DNA polymerase δ

• DNA polymerase γ

• DNA polymerase β

• DNA polymerase α

What is the function of PCNA in eukaryotic DNA replication?

• Unwinding DNA strands

• Synthesizing RNA primers

• Acting as a sliding clamp

• Proofreading DNA strands

What is the role of Rnase H and FEN1 in eukaryotic DNA replication?

• Removal of RNA primers

• Gap filling in DNA repair

• Joining ends of DNA segments

• Catalyzing removal of supercoils

What is the main function of RPA complex in eukaryotic DNA replication?

• Unwinding DNA strands

• Joining ends of DNA segments

• Synthesizing RNA primers

• Removing RNA primers

What is the function of telomerase in eukaryotic DNA replication?

• Unwinding DNA strands

• Removing RNA primers

• Synthesizing RNA primers

• Elongating telomeres

What is the structure of a telomere?

• Double-stranded DNA

• Single-stranded DNA

• RNA-DNA hybrid

• Loop stabilized by protein

What problem does telomere shortening lead to in eukaryotic DNA replication?

• Inability to divide

• Shortening of DNA strands

• Formation of supercoils

• Loss of DNA segments

What is the complex responsible for replacing lost ends of telomeres in eukaryotic DNA replication?

• RPA-PCNA complex

• FEN1-DNA Ligase 1 complex

• ORC-MCM complex

• Tert-Terc complex