Quiz: Prions

Type your name.

Where is scrapie endemic to?

• Germany
• Papua New Guinea
• France
• England
• Worldwide (meaning it is not endemic to any one place but can occur anywhere in the world.)

Where is CJD endemic to?

• Germany
• Papua New Guinea
• France
• England
• Worldwide (meaning it is not endemic to any one place but can occur anywhere in the world.)

What was the original cause for the emergence of BSE?

• from eating dead BSE cows
• from a genetic mutation
• from eating contaminated grass
• from eating Scrapie sheep

In the United States, what group possibly faces the danger of a prion disease?

• Cow farmers
• Deer hunters
• Sheep herders
• Horse riders

How did Kuru emerge?

• Kuru was a genetic mutation that occurred in the Fore tribe.
• The Fore tribe were cannibals and it came from eating members of other tribes that were their enemies.
• The sheep in Papua New Guinea were infected with Scrapie.
• A member in the Fore tribe randomly came down with CJD and when they died, they were eaten by their family members.

Why were children and women affected more than any other group with Kuru?

• They had compromised immune systems
• Men never participated in the ceremonial eating
• They were the only ones who handled the dead bodies and cut up the bodies
• They were the ones who ate the brains of those infected

List the order of prion diseases from NEWEST to OLDEST.

• Scrapie, Kuru, BSE, vCJD
• Scrapie, BSE, Kuru, vCJD
• vCJD, BSE, Kuru, Scrapie
• vCJD, BSE, Scrapie, Kuru

All of the following are true statements about prions except

• it is an acronym which stands for proteinaceous infectious particle
• they do not trigger an immune response in humans
• they contain DNA as its genetic material
• they normally occur in mammalian nerve cells

All of the following are true of prion proteins except:

• The shape of the protein determines the function of the protein
• Normal and abnormal prions have the same function
• Changing the shape of a protein also changes the function of that protein
• Normal and abnormal prions have different functions