OSPE PK Hemato-Onco (Blood Tests)

The following is true about "bleeding time test"

• Used to assess extravascular hemostatic factors

• Affected by capillary wall fragility

• Affected by amount of thrombocyte found in blood

• Used to assess the ability of blood vessel and thrombocyte to stop bleeding

Clotting time can be measured using the following test(s):

• Prothrombin time

• Activated Partial Thromboplastin Time

• Capillary tube (Duke) method

• Rumple-Leede test

The method used to test for capillary wall fragility is called:

(a)  

Reorder the following:

a. Platelet aggregation

b. Coagulation

c. Release of cytoplasmic granules

d. Vasoconstriction/spasm

e. Platelet adhesion/plug formation

(a)  

The following is part of primary hemostasis

• Platelet plug formation

• Coagulation

• Release of serotonin, ADP and thromboxane A2

• Platelet aggregation

The following is part of the extrinsic mechanism

• Factor III --> factor IIIa

  factor IIIa activates factor VII --> VIIa

• Factor XII --> factor XIIa

  Factor XIIa activates factor XI --> XIa

• Factor VIII --> factor VIIIa

  factor VIIIa and XIa activates factor X --> Xa