B cell activation stopp @ slide 16

Each B cell has Ig receptors of a single antigen specificity.

• True

• False

Mature B cells circulate in the blood, lymph, and lymphoid organs until they encounter antigen.

• True

• False

When a B cell is stimulated by an antigen, it will ____

• phagocytize the antigen and die

• create many clones bearing the same Ag receptor

Answer explanation

clonal selection and expansion

Selected B cell clones will become ____

• plasma cells

• memory B cells

Answer explanation

both will bear the same antigen receptor

Which cell takes antigen to draining lymph nodes and activate antigen-specific naive Tcells?

• macrophages

• DCs

T cells proliferate and differentiate into ___

• plasma cells

• effector T cells

stay in the LN and interact with activated B cells

• TH1

• TFH

• cytotoxic T cells

Which antibody is made first?

• high affinity IgM

• low affinity IgM

Memory B cells are generated to provide long term protection

• True

• False

The part of antigen that an antibody/BCR binds

• epitope

• TCR