Lectures 38-42 CMB3

What is the primary symptom of Cerebellar Dysfunction?

• Progressive choreiform movement disorder

• Ataxia

• Dystonia

• Bradykinesia

Which disorder is characterized by "progressive choreiform movement disorder"?

• Parkinson's

• Huntington's

• Wilson's

• Sydenham's Chorea

What is the cause of Wilson's disease?

• Autoimmune disorder caused by strep

• Genetic expanded CAG repeat

• AR disorder of copper excretion

• Loss of dopaminergic neurons in substantia nigra

Which of the following is a characteristic of Parkinson's disease?

• Sudden, unpredictable movements

• Resting tremor and bradykinesia

• Dance-like movements, fluid or jerky

• Tics causing sudden, brief action

What is the typical age of onset for Sydenham's Chorea?

• Before age 15, usually female

• After use of dopamine-blocking agent

• Years after onset of epilepsy

• Any age, no specific onset

Which treatment is commonly used for Parkinson's disease?

• Antipsychotics

• Dopamine agonists

• Sedatives

• Acetylcholine blockers

What is the main feature of Myoclonus?

• Tremor with action or suspension, not at rest

• Sudden, unpredictable, not suppressible

• Progressive choreiform movement disorder

• Orofacial movements

Which disorder is an autoimmune disorder caused by strep?

• Wilson's

• Huntington's

• Sydenham's Chorea

• Tourette's

What is the pathophysiology of Huntington's disease?

• Loss of dopaminergic neurons in substantia nigra

• Genetic expanded CAG repeat

• Autoimmune disorder caused by strep

• AR disorder of copper excretion

Which of the following is a treatment option for Tardive Dyskinesia?

• Dopamine agonists

• Dopamine blockers

• Sedatives, antiepileptics

• Acetylcholine blockers