Lung cancer

Which of the following suggestive of adenocarcinoma?

• TTF1+ve

• p40+ve

• Napsin A -ve

• CK7-ve

________ are used for staging of lung cancer.

I - American Joint Committee on Cancer (AJCC) 8th edition

II - Veterans’ Administration Lung Study Group (VALSG) two-stage classification

III - TNM staging

• I only

• I & III only

• III only

• I, II & III

Which is the best method of molecular profiling?

• RNA sequencing

• DNA sequencing

• IHC

• FISH

Workup for early lung cancer includes:

I - PET scan

II - MRI brain

III - Mediastinal staging

IV - Biopsy

V - Spirometry

VI - Echocardiography

• I & II

• I, II & III

• I, II, III & IV

• I, II, III, IV & V

• I, II, III, IV, V & VI

Surgical treatment of lung cancer depends on:

I - Tumour type

II - Staging

III - Spirometry

IV - Comoorbidity

• I & II

• II & III

• II, III & IV

• I, II, III & IV

Adjuvant_________ improves disease free survival.

• Chemotherapy

• Radiotherapy

• Targeted therapy

• Immunotherapy

Chemo-radiation is the standard of care for all unresectable stage III lung cancer.

• True

• False

__________ have the best overall survival to-date.

• EGFR TKI

• ALK TKI

• Immunotherapy

• Chemotherapy

Whole brain radiotherapy is the standard of care for all brain metastases.

• True

• False

Which of the patients will most likely benefit from immunotherapy?

• EGFR Exon 19 del;

  PDL-1 > 50%

• EGFR Exon 21 L858R;

  PDL-1 > 90%

• EGFR wild type;

  PDL-1 > 50%

• EGFR wild type;

  PDL-1 1 -49%