Intro: Virology Exam Questions (Chapter 8)

Which of the following is not a characteristic of enteroviruses?

• A) Oral–fecal transmission

• B) Icosahedral capsid

• C) (+) sense RNA

• D) Enveloped

Which of the following treatments would inactivate polio?

• A) Protease

• B) Chloroform

• C) pH less than 3

• D) Aldehyde

Which virus is primarily associated with meningitis and encephalitis?

• Echovirus type 11

• Poliovirus

• Coxsackievirus B

• Enterovirus D68

What would happen if the RNA genome of poliovirus was transfected into mouse cells?

• A) Nothing

• B) The RNA genome would be converted into DNA.

• C) The RNA genome would be converted from negative-sense to positive-sense.

• D) The RNA genome would be translated by host ribosomes into a polyprotein.

Which form of poliomyelitis results from viral invasion of the motor neurons of the anterior horn and is characterized by paralysis on one side of the body?

• A) Bulbar

• B) Subclinical

• C) Spinal

• D) Bulbospinal

6. A poliovirus with a mutated VPg would be unable to:

• A) cleave the viral polyprotein.

• B) initiate replication.

• C) attach to host cells.

• D) uncoat.

Which of the following is not a characteristic of the Sabin vaccine?

• A) Contains three serotypes of vaccine virus

• B) Requires booster vaccinations

• C) Sheds in stool weeks following vaccination

• D) Can cause vaccine-associated paralytic polio

8. Which viral infection may cause earaches and sinusitis and exacerbate asthma?

• 1. A) Coxsackie virus

• B) Rhinovirus

• C) Enterovirus

• D) Echovirus

9. Which country accounted for the majority of wild-type polio cases in 2014 and 2015?

• A) India

• B) Congo

• C) Pakistan

• D) Nigeria

10. Where did the first major outbreak of poliovirus in the United States occur?

• A) Vermont

• B) New York

• C) Texas

• D) Florida