Predictive Methods Using DNA Sequences Quiz-5

What is a major drawback shared by most gene identification programs?

• They are not trained on test data

• They work best on things similar to what they have seen before

• They do not require predicting both a discrete beginning and an end to a gene

• They are not influenced by G + C content

Which method is recommended as a starting point for incompletely assembled sequence contigs?

• GENSCAN

• HMMgene

• MZEF

• GRAIL

What is the advantage of using GeneMachine for gene prediction?

• It requires users to install local copies of the prediction programs

• It provides slower performance

• It does not allow annotations to be made to the results

• It allows users to query multiple exon and gene prediction programs in an automated fashion

Which program allows users to simultaneously run a number of prediction methods and homology searches, as well as providing the ability to annotate sequence features through a graphical user interface?

• GRAIL

• FGENES

• GeneParser

• Genotator

What is the main feature of GeneMachine?

• It provides slower performance

• It requires users to install local copies of the prediction programs

• The process is fully automated

• It does not allow annotations to be made to the results

What is the significance of using BLAST and FASTA in gene identification?

• They do not require users to supplement predictions with results from at least one other predictive method

• They target both dbEST and the protein databases for homology-based clues

• They are not considered an absolute requirement

• They provide slower performance

What is the purpose of using PROCRUSTES in gene identification?

• To annotate sequence features through a graphical user interface

• To run multiple exon and gene prediction programs in an automated fashion

• To find repeats within the query sequence

• To supplement predictions with results from at least one other predictive method

What is the role of the Human Genome Project in facilitating gene identification?

• It will not contribute to the advancement of gene identification methods

• It will provide biological information that can be used to develop better methods, yielding more accurate predictions

• It will not be used to develop better methods for gene identification

• It will not play a major role in facilitating similar efforts targeting other model genomes