
Predictive Methods Using DNA Sequences -3
Passage
•
Biology
•
12th Grade
•
Practice Problem
•
Hard
Wayground Content
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8 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the accuracy of PROCRUSTES in predicting correct gene structures when using candidate proteins?
90%
75%
50%
99%
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the purpose of GenomeScan program?
To predict gene structures based on DNA sequence alone
To assign a higher score to putative exons that overlap BLASTX hits
To analyze nonstandard gene structures
To identify protein sequences in the public databases
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the main function of the Type column in the GENSCAN output table?
Provides the probability value of the prediction
Shows the direction of the prediction
Indicates the length of the prediction
Specifies the type of prediction (e.g., initial exon, internal exon)
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the accuracy of GENSCAN exons with a very high probability value (P > 0.99) when matching a true, annotated exon?
50%
75%
88.1%
97.7%
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the purpose of the GenomeScan program when a moderate or closely related protein sequence is available?
To improve the accuracy of gene structure prediction
To predict gene structures based on DNA sequence alone
To assign a lower score to putative exons
To ignore regions of high detected similarity
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What does the algorithm of PROCRUSTES require before making a prediction?
Public databases
DNA sequence with content-based signals
BLASTX hits
Candidate proteins
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the significance of the phrase 'he who stretches' in the context of Greek mythology?
Symbolizes the idea of forcing something to fit
Represents the accuracy of gene prediction
Describes the hero Theseus
Refers to a bandit with a warped idea of hospitality
8.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the main advantage of using candidate proteins in the PROCRUSTES algorithm?
Reduces the need for spliced alignment algorithm
Increases the number of predicted exons
Provides information about public databases
Improves the accuracy of gene structure prediction
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