Predictive Methods Using DNA Sequences -4

Which method uses a rule-based system to examine putative exons and assemble them into the most likely gene for a given sequence?

• PROCRUSTES

• HMMgene

• GenelD

• GeneParser

Which method uses position-weight matrices to assess whether a given stretch of sequence represents a splice site or a start or stop codon?

• HMMgene

• GenelD

• GeneParser

• PROCRUSTES

Which method computes scores on all subintervals in a submitted sequence and uses a neural network approach to determine whether each subinterval contains a first exon, internal exon, final exon, or intron?

• GeneParser

• PROCRUSTES

• GenelD

• HMMgene

Which method predicts whole genes in any given DNA sequence using a hidden Markov model method?

• GeneParser

• HMMgene

• PROCRUSTES

• GenelD

What is the best gene structure prediction program according to the comparisons made by Jean-Michel Claverie?

• GeneParser

• GenelD

• PROCRUSTES

• HMMgene

What measure reflects the fraction of actual coding regions that are correctly predicted as truly being coding regions?

• Sensitivity

• Specificity

• Correlation Coefficient

• True Negative