Understanding Pedigrees and Genetic Inheritance

What shape represents males in a pedigree?

• Rectangle

• Triangle

• Square

• Circle

What does a half-filled shape indicate in a pedigree?

• Unaffected individual

• Unknown status

• Affected individual

• Carrier of the trait

Which inheritance pattern shows affected individuals in most generations?

• Autosomal dominant

• Mitochondrial

• Autosomal recessive

• X-linked recessive

In autosomal recessive inheritance, what is the chance of disease in children if both parents are carriers?

• 100%

• 50%

• 75%

• 25%

How is X-linked recessive disease inherited?

• From father to son

• From mother to daughter

• From father to daughter

• From mother to son

What percentage of sons will be affected if the mother is a carrier of an X-linked recessive disease?

• 100%

• 0%

• 50%

• 25%

Does this pedigree show a dominant or recessive trait?

• Dominant
• Recessive

Huntington's Disease is a dominant trait.
What is the correct genotype for individual I-2?

• HH
• Hh
• hh
• H_

If this pedigree shows an autosomal recessive disorder, what MUST the genotype of individual II-3 be?

• HH
• Hh
• hh
• None of the above

Objective #13

This is a pedigree that follows blue eyes which is a recessive trait. What is the genotype of the father (square) in generation 1?

• Aa

• AA

• aa

• A?