HaemBytes 1

Possible Differentials / Thoughts ?

What seems to be the best initial Simple Set of investigations to kick start the diagnostic process?

• FBC

  Autoimmune Screen

  CRP

  Iron

  JAK2

  Blood Film

• FBC

  Iron Profile / Ferritin

  LDH

  ESR

  CRP

  Blood Film

• FBC

  Iron Profile / Ferritin

  LDH

  ESR

  CRP

  Blood Film

  Extra EDTA for JAK2 if required

• FBC

  Autoimmune Screen

  CRP

  Iron

  JAK2

  Blood Film

  Immunoglobulins

What would you be thinking in terms of potential causes for this presentation

Which Translocation is Normally associated with M3 AML

• t 15:17

• t 8:21

• t14:18

• t 8:14

What investigations will be helpful in your initial workup for this patient?

What are you thinking when you see this History and Initial Blood Tests?