BDT Y1 SEM 2 TUTORIAL 2

The most common mechanism of vascular leakage in acute inflammation is

• Retraction of endothelial cells

• Transcytosis

• Endothelial injury

• Angioneogenesis

Cardinal signs of acute inflammation include(s)

• Redness

• Swelling

• Hypotension

• Hypothermia

• Loss of function

Leukocyte migration through endothelium is called

• Rolling

• Adhesion

• Diapedesis

• Chemotaxis

The outcomes of acute inflammation include(s)

• Complete resolution

• Healing by connective tissue replacement

• Metastasis

• Hyperplasia

• Chronic inflammation

The process where leukocytes engulf and digest bacteria

• leukocytosis

• pathogenesis

• hydrostatic pressure

• phagocytosis

A 30 years old fire fighter has extensive third degree burn at arms and hands.

This patient has high risk of developing which type of complication of wound

healing?

• Ulceration (presence of ulcer)

• Keloid (scar)

• Contracture (shortening of muscle or joint)

• Dehiscence (opening or splitting in tissues)

Edema can be cause by following except

• An increased capillary hydrostatic pressure.

• Lymphatic obstruction.

• Sodium and water retention.

• An increased in plasma protein concentration.

• An increased capillary permeability.

A 47-year-old male presents with pain in the midportion of his chest.

The pain is associated with eating and swallowing food. Endoscopic examination

reveals an ulcerated area in the lower portion of his esophagus. Histologic

sections of tissue taken from this area reveal an ulceration of the

esophageal mucosa that is filled with blood, fibrin, proliferating blood vessels,

and proliferating fibroblasts. Mitoses are easily found, and most of the

cells have prominent nucleoli. The most correctly

describes this ulcerated area.

• Caseating granulomatous inflammation

• Dysplastic epithelium

• Granulation tissue

• Noncaseating granulomatous inflammation

Answer explanation

Tissue repair occurs through

the regeneration of damaged cells and the replacement of tissue by connective

tissue. Tissue repair involves the formation of granulation tissue,

which histologically is characterized by a combination of proliferating

fibroblasts and proliferating blood vessels.

A 45 year-old ambassador of Kenya in Pakistan comes to you with a raised scar at the site of a wound that he sustained in a road traffic accident last year. The scar grows beyond the margins of
the original wound and is very ugly looking. The most probably cause isis?

• Lack of wound remodeling

• Excess formation of repair components

• Wound remodelling

• Contracture formation

The chemical mediator that involved in giant cell granulomatous inflammation is

• Prostaglandin

• Bradykinin

• Nitric oxide

• Interferon y