NeuroPsychoPharmacology Lab PG 2024

What is the primary purpose of using the spontaneous alternation y-maze in this study?

• To measure long-term memory in young rodent models

• To assess behavioral outcomes and understand mechanisms of impairment

• To evaluate the locomotion abilities of aged mice

• To study the effects of dietary supplements on rodent behavior

Which of the following is a key step to ensure accurate results during the y-maze testing?

• Testing animals at random times each day
  

• Using loud noises to stimulate the animals during testing
  

• Habituating the mice to the testing room 30 minutes prior to testing
  

• Using bright, direct lighting in the testing room

What is the correct calculation for the percentage of alternation in the y-maze test?

• Number of arms entered / Total number of alternations × 100%

• Total number of alternations / Number of arms entered × 100%

• Number of arms entered × Total number of alternations × 100%

• Total number of arm entries / Total time spent in the maze × 100%

Which of the following statements correctly describes the purpose of the Open Field Test (OFT)?

• To measure the long-term memory retention in rodents

• To evaluate locomotor and exploratory activity, as well as anxiety-like behavior in rodents

• To assess the social interaction patterns in rodents

• To determine the nutritional preferences of rodents

What is a critical precaution to minimize external distractions during the OFT?

• Performing the test during the rodent's inactive phase

• Using strong lighting to increase exploration

• Conducting the test in a quiet and isolated environment

• Cleaning the arena with a strong detergent before each test

Which parameter is used to evaluate anxiety-like behavior in rodents during the OFT?

• Total distance traveled

• Number of grooming sessions

• Time spent in the center and periphery of the arena

• Time spent eating food provided in the arena

What is the primary principle behind the Elevated Pulse Maze (EPM) in assessing anxiety-like behavior in rodents?

• Rodents prefer open, elevated spaces over enclosed areas

• Rodents exhibit increased grooming behavior in elevated spaces

• Rodents avoid open, elevated spaces and prefer enclosed areas

• Rodents show increased locomotor activity in enclosed areas

Which of the following parameters is NOT typically measured in the Elevated Pulse Maze (EPM) test to assess anxiety-like behavior in rodents?

• Time spent in open and enclosed arms

• Number of entries into each arm

• Total distance traveled in the maze

• Frequency of grooming behavior

Which software program is mentioned for generating heatmaps and visualizing the behavior of rodents in the EPM test?

• Med Associates Activity Monitor

• ANY-maze

• Noldus EthoVision

• GraphPad Prism

What condition is primarily assessed using the Sucrose Preference Test (SPT) in rodents?

• Anhedonia

• Hyperactivity

• Aggression

• Cognitive dysfunction