LC Determination and Analysis Quiz

In LC-MS/MS, what does the term "MS/MS" refer to?

• Tandem mass spectrometry

• Single mass spectrometry

• Dual separation method

Which compartment is considered as the "heart" of LC?

• Pumps

• Autosampler

• Column

• Degasser

What is the typical order of the steps in an LC-MS analysis?

• A. Separation, Detection, Ionization

• B. Detection, Separation, Ionization

• C. Ionization, Separation, Detection

• D. Separation, Ionization, Detection

In reversed-phase liquid chromatography, which compounds elute first from the column?

• A. Compounds with high polarity

• B. Compounds with low polarity

• C. Compounds with high molecular weight

• D. Compounds with low molecular weight

What is the primary function of the column in liquid chromatography?

• To detect ions

• To separate the components of a mixture

• To ionize the sample

• To measure mass-to-charge ratios

In reversed-phase chromatography, what is the nature of the stationary phase?

• Polar

• Non-polar

In normal phase chromatography, what is the nature of the stationary phase?

• Non-polar

• Polar

What is "retention time" in liquid chromatography?

• The time a compound spends in the mass spectrometer

• The time taken to detect an ion

• The time taken for a compound to pass through the column

This is a...

• pole

• detector

• column