VIII.3. Nuclear Medicine: Diagnosis and Therapy (LO 6)

1) What is the primary quantity measured in internal dosimetry?

• A) Exposure rate

• B) Absorbed dose

• C) Radiation intensity

• D) Radiopharmaceutical concentration

2) The MIRD schema for dose calculations was originally published by which organization?

• A) International Atomic Energy Agency (IAEA)

• B) Society of Nuclear Medicine

• C) World Health Organization (WHO)

• D) International Commission on Radiological Protection (ICRP)

3) Which of the following is NOT a factor affecting the calculation of the absorbed dose in nuclear medicine?

• A) Distribution of radionuclide within the body

• B) Biological half-life of the radionuclide

• C) Patient's body temperature

• D) Uptake of radionuclide in critical organs

4) Which method is mentioned as impractical for calculating the absorbed fraction of radiation in internal dosimetry?

• A) Monte Carlo simulation

• B) Analytical calculation

• C) Point source measurement

• D) Use of reference models

5) What is the purpose of Monte Carlo simulations in radiation transport?

• A) To simulate patient behavior

• B) To estimate energy fluence or dose at each point

• C) To measure physical decay rates

• D) To design new radiopharmaceuticals

6) In the MIRD schema, what does the S-factor represent?

• A) Source strength

• B) Absorbed dose rate per unit activity

• C) Radionuclide decay constant

• D) Patient size coefficient

7) Why is a patient-specific approach necessary for radionuclide therapy dosimetry?

• A) To comply with international regulations

• B) To account for patient-specific organ geometry and dose distribution

• C) To reduce the cost of treatment

• D) To simplify the dosimetry process for clinicians