Coagulation Tests and Pathways

What does PT (Prothrombin Time) primarily measure?

• Intrinsic pathway

• Extrinsic pathway

• Platelet function

• Fibrinolysis

The aPTT test evaluates the functionality of which pathway of the coagulation cascade?

• Extrinsic pathway

• Intrinsic pathway

• Fibrinolytic pathway

• Common pathway only

Which test is commonly used to monitor patients on warfarin therapy?

• aPTT

• PT/INR

• TT

• D-dimer

The aPTT test is prolonged in which of the following conditions? A. Hemophilia A and B B. Vitamin K deficiency C. Liver disease D. Thrombocytopenia

• Hemophilia A and B

• Vitamin K deficiency

• Liver disease

• Thrombocytopenia

Thrombin Time (TT) specifically measures (a)   .

• Fibrinogen to fibrin conversion
• Platelet aggregation
• Extrinsic pathway
• Intrinsic pathway

Match the following conditions with their corresponding effects on PT.

• Deficiency leading to clotting issues

• Hemophilia A

• Indirect thrombin inhibitor

• Warfarin therapy

• Causes prolonged PT

• Factor XIII deficiency

• Inhibits vitamin K

• Heparin therapy

A patient with a deficiency in Factor VIII would most likely show which abnormality in their lab results?

• Prolonged PT

• Prolonged aPTT

• Prolonged TT

• Normal PT and aPTT

Which laboratory test is used to monitor unfractionated heparin therapy?

• PT

• aPTT

• TT

• Bleeding time

In the presence of disseminated intravascular coagulation (DIC), which tests are typically prolonged?

• PT and aPTT only

• aPTT and TT only

• PT, aPTT, and TT

• Bleeding time only

Which test evaluates the final step in the coagulation cascade?

• Conversion of fibrinogen to fibrin

• Conversion of prothrombin to thrombin

• Platelet aggregation

• Function of Factor VII