Complement Cascade Quiz

What initiates the formation of the C1 complex in the complement cascade?

• Antigen binding to IgG

• C3 hydrolysis

• C5 cleavage

• Membrane attack complex formation

Which pathway is involved in the formation of C3 convertase?

• Classical pathway

• Alternative pathway

• Both classical and alternative pathways

• Neither pathway

What is the result of C3 hydrolysis in the complement cascade?

• Formation of C3 convertase

• Cleavage of C5

• Production of C3b and C3a fragments

• Formation of the membrane attack complex

What does C3b cleave in the complement cascade?

• C2

• C4

• C5

• C9

Which components form the cylindrical membrane attack complex?

• C3b, C3a

• C5b, C6, C7, C8, C9

• C2a, C4b

• C1 complex

What happens to the cell at the end of the complement cascade?

• It divides

• It swells and bursts

• It shrinks

• It becomes dormant

Which fragment is not directly involved in forming C3 convertase?

• C2a

• C4b

• C3b

• C5b

What is the role of C3 convertase in the complement cascade?

• Initiates antigen binding

• Hydrolyzes C3

• Forms the membrane attack complex

• Cleaves C5

Which of the following is a fragment produced by C3 hydrolysis?

• C5a

• C3a

• C4b

• C2a

What is the function of C5b in the complement cascade?

• Initiates C1 complex formation

• Forms part of the membrane attack complex

• Hydrolyzes C3

• Cleaves C2