protein and enzyme

An enzyme and substrate can be compared to

• lock and key

• a faucet

• a door hinge

• light switch

What type of macromolecule are enzymes?

• Protein
• Carbohydrate
• Lipid
• Nucleic Acid

What is another name for a protein?

• fat

• sugar

• amino acid

• polypeptide

What 3 letters do enzymes typically end in?

• -ose
• -ase
• -ese
• -tic

Which of the following conclusions can be drawn from this graph?

• The optimum pH of the enzyme is 6.6.
  
• The optimum pH of the enzyme is 5.8
  
• The enzyme’s activity increases as pH increases 5.0 to 9.0
  
• The enzyme’s activity is greater around pH of 8.0 .
  

How does an enzyme's activity change with increasing concentration of substrate?

• decreases
• stays the same
• no change
• increases 

What makes an enzyme substrate specific?

• Size
• Shape
• Name
• Location it is found in

In competitive inhibition, an inhibitor:

• A) binds at several different sites on an enzyme.

  
  

• B) binds covalently to the enzyme.

  
  

• C) binds only to the ES complex.

  
  

• D) binds reversibly at the active site.

  
  

• E) lowers the characteristic Vmax of the enzyme.

  
  

Vmax for an enzyme-catalyzed reaction:

• A) generally increases when pH increases.

  
  

• B) increases in the presence of a competitive inhibitor.

  
  

• C) is limited only by the amount of substrate supplied.

  
  

• D) is twice the rate observed when the concentration of substrate is equal to the Km.

  
  

• E) is unchanged in the presence of a uncompetitive inhibitor.

  
  

A good transition-state analog:

• A) binds covalently to the enzyme.

  
  

• B) binds to the enzyme more tightly than the substrate.

  
  

• C) binds very weakly to the enzyme.

  
  

• D) is too unstable to isolate.

  
  

• E) must be almost identical to the substrate.