Chapter X

What will happen to a sequence targeted by a miRNA?

• mRNA with a similar sequence will be bound by RISC and unavailable for translation

• mRNA with that sequence will be exported out of the cell

• DNA with that sequence will be methylated by RITS

•  

  mRNA with that sequence will be alternatively spliced

What can prevent deadenylation-dependent decay of an mRNA?

• RNA Methylation

• DNA splicing

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  Binding of poly-A binding protein

• Alternative splicing

Which of the following is NOT involved in cytoplasmic polyadenylation?

•  

  RNA polymerase I

•  

  poly-A specific Ribonuclease (PARN)

• Maskin

•  

  cytoplasmic polyadenylation element binding protein (CPEB)

The Dicer protein does what?

•  

  Cuts double stranded DNA to make CRISPR arrays

•  

  Destroys tRNAs bond by RISC

•  

  Cuts double stranded RNA to make small RNAs

•  

  Cuts out introns during splicing

A researcher is studying plant development. She isolates a mutant and discovers that the piece of DNA that is mutated does not code for a protein. However, this piece of DNA is complimentary to a gene known to function in early embryonic plant development. The mutant she identified most likely functions as a(n) ________.

•  

  general transcription factor known to regulate many different genes

•  

  microRNA (miRNA)

• intron

•  

  ribosomal RNA (rRNA)

A sister is heterozygous for a genetic disorder while her brother is homozygous for the disease allele. She has a child with the disorder but none of her brother's children have the disease. What is the best explanation for this?

• Paternal Imprinting

• Maternal Imprinting

• Incomplete Dominance

• Incomplete Penetrance

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

Imprinting patterns are re-programmed in ____cells

• Germ line

• Adult Stem Cells

• Stomatic Cells

• Differentiated cells

The random inactivation of autosomal genes is associated with the_____ of the histone____

• Di-methylation;H3

• Tri-methylation; H2B

• Di-methylation; H2B

• Tri-methylation; H3

Why do nutrients like folic acid, vitamin B12, and choline have a particularly strong effect on epigenetic marks?

• The bind phosphorylated histones together 

•  

  They are used to build histones

•  

  They bind to acetylated histones

•  

  They are used to make cofactors used in methylation reactions

Imprinting is mainly facilitated by what type of epigenetic mark?

• DNA methylation

• Histone methylation

• Histone phosphorylation

• Histone acetylation