Introduction to Alkyl Halides

1. Which alkyl halide has the highest reactivity for a particular alkyl group?

• R-F

• R-Cl

• R-I

• R-Br

Write the order of increasing S₁N reactivity for the following alkyl halides:

A) CH3-X

B) (CH3)2CH-X

C) (CH3)3C-X

D) (CH3)3C-CH2-X

• a) A>C>B>D

• b) C>A>B>D

• c) C>B>D>A

• d) D>C>B>A

3. Which of the following is not the method of preparation of alkyl halide?

• a) Darzen’s method

• b) Halogenation of alkene

• c) Addition of HX on alkenes

• d) Hydration of alkene

Toluene reacts with a halogen in the presence of iron (III) chloride giving ortho and para halo compounds. The reaction is

• Electrophilic elimination reaction

• Electrophilic substitution reaction

• Free radical addition reaction

• Nucleophilic substitution reaction

Chlorobenzene is formed by reaction of chlorine with benzene in the presence of AlCl3. Which of the following species attacks the benzene ring in this reaction?

• Cl^-

• Cl⁺

• AlCl₃

• [AlCl₄]^-

Which of the following reactions can be used to fluorinate a compound?

• Sandmeyer’s reaction

• Darzen’s reaction

• Hunsdicker reaction

• Swartz reaction

If a substrate undergoing S₂N reaction was of one stereoisomer, what would the product be like?

• .A racemic mixture

• One stereoisomer

• An unequal mixture of enantiomers

• A non-chiral compound

Ethylidene chloride is a/an ______________.

• vic-dihalide

• gem-dihalide

• allylic halide

• vinylic halide

. Which is the correct increasing order of boiling points of the following compounds?

• Bromobenzene < 1-Bromobutane < 1-Bromopropane < 1-Bromoethane

• Bromobenzene < 1-Bromoethane < 1-Bromopropane < 1-Bromobutane

• 1-Bromopropane < 1-Bromobutane < 1-Bromoethane < Bromobenzene

• 1-Bromoethane < 1-Bromopropane < 1-Bromobutane < Bromobenzene

Which reagent will you use for the following reaction?

CH₃CH₂CH₂CH₃ → CH₃CH₂CH₂CH₂Cl + CH₃CH₂CHClCH₃

• Cl₂ /UV light

• NaCl + H₂SO₄

• Cl₂ gas in dark

• Cl₂ gas in the presence of iron in dark