AP Bio Insta-Review Topic 4.7: Regulation of Cell Cycle

Which checkpoint determines whether the cell will divide?

• G₁

• S

• G₂

• M

Which checkpoint inhibits nondisjunction?

• G₁

• S

• G₂

• M

Which checkpoint verifies DNA has “no errors” and replicated?

• G₁

• S

• G₂

• M

What is the function of a kinase?

Answer explanation

Kinase is an enzyme that adds phosphate

Protein kinase is responsible for the phosphorylation cascade in transduction

Cyclin dependent kinase will phosphorylate proteins needs for cell division

Describe the association between cyclin and CdK.

Answer explanation

Cyclin is produced during interphase. CdK is maintained at high levels in the cell. When the cyclin level reaches a certain amount, it will activate the CdK and allow for the progression into the M phase. This specific CdK is called MPF. Maturation Promoting Factor

(but let’s just call it mitosis promoting factor since you need it to enter mitosis)

Tags

NGSS.HS-LS1-4

What happens if the cell incorrectly bypasses a checkpoint?

Answer explanation

› Cancer

› Apoptosis

Tags

NGSS.HS-LS1-4

What phase is the M checkpoint located in?

• Anaphase

• Metaphase

• Prophase

• Telophase

Tags

NGSS.HS-LS1-4

How does the level of cyclin and CdK vary during cell cycle?

• Cyclin increases, CdK remains the same

• Cyclin decreases, CdK remains the same

• Cyclin remains the same, CdK levels increase

• Cyclin remains the same, CdK levels decrease

Tags

NGSS.HS-LS1-4

Proto-oncogenes can mutate into oncogenes

• True

• False

Tags

NGSS.HS-LS3-2

If the cell doesn’t get the go ahead signal in G1, where does it go?

• G₀

• G₁

• G₂

• S