Sickle Cell Disease Genetics

What protein is affected by sickle cell disease?

• Red Blood Cells

• Hemoglobin

• White Blood Cells

• DNA

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

Which combination would result in a 50% chance of having sickle cell disease?

• SS + SS

• Ss + SS

• Ss + ss

• Ss + Ss

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

Why do sickle cell anemia patients experience pain?

• Sickled red blood cells cause blockages

• The sickled blood cells are carried throughout the body to fast

• Sickled blood cells attack normal blood cells

• There is a lower number of white blood cells

Where are the most sickle cell anemia patients located?

• Up North

• In the South

• Around the Equator

• In China

Why does sickle cell disease occur more often near the equator?

• Humidity makes it more likely to pass on

• Sickle cell disease provides defense against pellagra

• Sickle cell disease provides defense against malaria

• It's just random chance

Tags

NGSS.HS-LS4-2

What are treatment(s) for sickle cell anemia?

• Blood Transfusion

• Hydroxyurea

• Bone Marrow Transplant

• All of the Above

What chromosome does sickle cell disease affect?

• Chromosome 12

• Chromosome 11

• Chromosome 2

• Chromosome 21

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

Is person I-1 a carrier?

• Yes

• No

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

Person II-5 is not a carrier of sickle cell anemia

• True

• False

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

If person III-1 was to have a child with a carrier, what is the probability of that child having sickle cell anemia?

• 50%

• 100%

• 75%

• 25%

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2