AP Biology Unit 6 Biotechnology

The leading and the lagging strands differ in that

• the leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction.

• the leading strand is synthesized by adding nucleotides to the 3ʹ end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5ʹ end.

Based your answer on the figure: A mutation results in a defective enzyme A. Which of the following would be a consequence of that mutation?

• an accumulation of A and no production of B and C

• an accumulation of A and B and no production of C

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NGSS.HS-LS3-2

The genetic code is essentially the same for all organisms. From this, one can logically assume all of the following except

• a gene from an organism could theoretically be expressed by any other organism.

• all organisms have a common ancestor.

• DNA was the first genetic material.

• the same codons in different organisms usually translate into the same amino acids.

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NGSS.HS-LS1-1

NGSS.HS-LS4-1

RNA polymerase moves in which direction along the DNA?

• 3ʹ → 5ʹ along the template strand

• 3ʹ → 5ʹ along the coding (sense) strand

What are the coding segments of a stretch of eukaryotic DNA called?

• introns

• exons

Introns are significant to biological evolution because

• their presence allows exons to be shuffled.

• they protect the mRNA from degeneration.

A mutation in which of the following parts of a gene is likely to be most damaging to a cell?

• intron

• exon

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NGSS.HS-LS1-1

NGSS.HS-LS3-2

Alternative RNA splicing

• is a mechanism for increasing the rate of transcription.

• can allow the production of proteins of different sizes from a single mRNA

When does translation begin in prokaryotic cells?

• as soon as transcription has begun

• once the pre-mRNA has been converted to mRNA

Why might a point mutation in DNA make a difference in the level of proteinʹs activity?

• It might substitute an amino acid in the active site.

• It might exchange one stop codon for another stop codon.

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NGSS.HS-LS3-2